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Fractional CFO & Accounting Solutions for Life Sciences Companies

Whether you’re preparing for clinical trials, raising capital, or planning an acquisition, our team delivers the specialized financial expertise life sciences companies need to move forward with confidence.

4.9 Stars

Average Client Rating

On independent review site ClearlyRated, G-Squared Partners has a rating of 4.9 Stars with reviews from 50+ clients. 

87

Net Promoter Score

In our 2025 Client Survey, we achieved a NPS of 87: significantly higher than the accounting industry average of 39.

9 out of 10

Would Recommend G-Squared Partners

Nearly 9 out of 10 clients would recommend us to a friend or colleague.

Transforming Cutting-Edge Science Into Commercial Success

Life sciences companies don’t follow the rules of traditional accounting. Long R&D timelines, complex clinical trial accruals, milestone-driven partnerships, and evolving regulatory requirements make it difficult to present a clear financial picture. Without the right systems in place, even the most promising scientific breakthroughs can stumble when it comes time to raise capital or prepare for an exit.

At G-Squared Partners, we understand the financial realities that biotech, pharma, medical device, and diagnostics companies face. Our team has guided life sciences businesses through these challenges—building the accounting infrastructure, financial models, and investor-ready reporting needed to secure funding, support compliance, and maximize valuation.

By combining deep industry expertise with hands-on CFO experience, we help founders and executives translate groundbreaking science into sustainable, investor-ready businesses.

Life Sciences

From R&D to Exit: Financial Solutions Built for Life Sciences Companies

Outsourced CFOs bridge the gap between finance and management, giving your leaders unparalleled financial insights that help them allocate resources more effectively, make smarter decisions, and build for a better future.

Premium Resource: Biotech Industry Accounting Guide: From Discovery to Exit

The biotech and life sciences industry is filled with opportunity, but also with financial challenges that can make or break success. From clinical trial accruals and grant funding to milestone-driven partnerships and exit readiness, the accounting decisions you make today will directly shape your company’s future.
That’s why we created our Biotech Industry Accounting Guide: From Discovery to Exit. This comprehensive guide walks you through:

  • Early-Stage Fundamentals: R&D expense management, revenue recognition for partnerships, and intangible asset decisions
  • Growth-Stage Management: Managing cash runway, complex financing, and building scalable systems
  • Strategic Exit Preparation: Financial readiness, due diligence, and valuation support for M&A
  • Transaction Execution: Navigating the M&A process and post-acquisition integration
  • Industry-Specific Challenges: Regulatory costs, commercial operations, and risk management
Whether you’re raising your first institutional round or preparing for acquisition, this guide will help you build financial infrastructure that attracts investors, supports compliance, and maximizes value.

 

Get it now

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The Financial Partner Life Sciences Leaders Trust

Life sciences companies don’t have time for generic accounting solutions. You need a partner who understands the realities of drug development, medical device regulation, diagnostics, and digital health — and how each financial decision shapes investor confidence and exit value.

At G-Squared Partners, our team combines:

  • Deep industry expertise: We’ve supported biotech, pharma, medtech, and diagnostics companies through every stage of growth.
  • Proven M&A experience: Over team has guided over 50 successful transactions.
  • Hands-on leadership: Our fractional life sciences CFOs have served in senior finance roles at high-growth companies, giving you practical, real-world guidance.
  • Finance team in a box: From bookkeeping through CFO-level strategy, we’re an all-in one solution that scales with your company as it grows.

The result: financial clarity, investor-ready reporting, and a stronger foundation for growth and exit.
Team-in-a-box-1

A "Go-To Firm for Outsourced CFO Services"

★★★★★

G-Squared Partners is our go-to firm for part-time CFO services. They provide value beyond the classic CFO responsibilities, including participating in strategy sessions, obtaining financing, identifying KPIs and getting significant transactions completed.

Osage Venture Partners

A "True Partner and Extension to our Team"

★★★★★

G-Squared is more than the outsourced financial services they provide to our organization. They continually work with us to align our strategic vision with the goals of the organization via deep industry expertise; a strong understanding of where markets are trending; and multifaceted experience in diverse industries. On more than one occasion, their forward-leaning guidance, as market conditions evolve, has avoided the pitfalls that have befallen our competitors. Partnership and results-driven outcomes are the cornerstones of our track record together.

David Stefanich, Founder/CEO

The only Firm to meet the Needs of Our Fast-Growing SaaS Company

★★★★★

After having tried multiple other service providers and platforms, G-Squared is the only firm that brings together the right combination of CFO, Accounting, and Bookkeeping services in a way that integrates naturally with my team and meets the needs of a fast-growing SaaS Company.

DataKwip, Inc.

They're a Member of Our Team

★★★★★

G Squared Partners has served as our CFO and accounting team for over 4 years. While the skill set and the professionals involved with our company have always been outstanding, what really stands out to me is their commitment to the company’s success. We don’t look at them as an outsourced service provider but as an integral member of the team. Just like we expect from any of our employees, they consistently do whatever it takes to complete a project on time regardless of the time pressures. When working with outside investors, due diligence exercises as well as general day-to-day managing the business, their efforts are a critical component of our success.

Powerlytics, Inc.

Schedule a Free 30 Minute Strategy Session

What to Expect:

  A high-level financial assessment of your business.
  Guidance on key financial challenges like cash flow, profitability, or scaling.
  Insights on how our Finance Team in a Box Solution can help you reach your goals. 
 

Ready to learn how we can help your business? Schedule your consultation today!

FAQs

Looking for more information? Here are some of the most common questions we hear from life sciences founders and executives. If you don’t see your question here, reach out to us — we’d be happy to talk.
What makes life sciences accounting different from other industries?
Biotech, pharma, and medical device companies face long development timelines, grant funding, and regulatory costs that don’t fit neatly into traditional accounting frameworks. These unique factors require specialized expertise to manage correctly. 
How can a fractional CFO help my life sciences company?
A fractional CFO provides strategic financial leadership without the cost of a full-time executive. For life sciences companies, this means building investor-ready models, managing cash runway, and preparing your company for fundraising and exit opportunities. 
What size companies do you typically work with?
We support early- to mid-stage life sciences companies, typically ranging from venture-backed startups through established and acquisition-ready businesses. Our solutions scale with your needs as your programs advance. 
Can you help prepare us for fundraising or an M&A exit?
Absolutely. We specialize in building financial infrastructure, reporting, and documentation that give investors and potential acquirers the confidence they need to commit. Our team has supported over 50 successful M&A transactions and has helped our clients raise over $600 million in equity and debt financing. 
Can you work with my existing systems and software?
Yes. We’re experienced with QuickBooks, Bill.com, Gusto, and other common platforms. We can work within your existing tech stack or recommend improvements.
What makes G-Squared Partners different from other firms?
Unlike traditional accounting firms focused primarily on compliance, our team is primarily focused on functioning as an extension of your existing accounting and finance team. Our leaders include former CFOs of publicly traded companies who have decades of combined experience in the manufacturing industry. We combine this industry experience with an unrelenting focus on precision and accuracy in our work, with multiple layers of review for all deliverables.